The DORIAN GRAY project is built on a dynamic and integrated approach.
At its core lies the development of a Digital Twin—a virtual version of the user that helps monitor health and behavior—combined with personalized guidance through virtual coaching sessions and interactive physical activities designed as games (exergames) to motivate movement and engagement.
After collecting and analyzing relevant health and lifestyle data, these combined systems will first be tested in a small-scale pilot study, and then gradually offered to a larger group of participants.
Ultimately, the goal of the project is to integrate the project's innovations into real-world medical practices, shaping future treatment and prevention strategies.
Health Data and AI Models
This leg of the project focuses on gathering and processing health data—such as imaging and biomolecular information—and using it to develop innovative digital tools.
AI models are created to explore the relationship between cardiovascular health and cognitive function. These models are then integrated into the PORTRAIT digital twin platform—a personalized virtual model that can support healthcare decision-making.
Patient Engagement Tools
To help patients stay engaged and motivated, as well as to monitor their health parameters, the project is developing two main AI-driven tools integrated with the digital twin platform.
Digital Coaching System
The avatar-based digital coaching system will be accessible via the MIRROR mobile app, which provides tailored health recommendations and encourages behavior change.
Exergaming System
This system will be aligned with the MIRROR app, which uses fun and interactive physical-cognitive games, guided by wearable technology, to promote better health outcomes.
Real-World Tests and Future Use
The systems will be tested on patients with cardiovascular risks and mild cognitive impairment across several European countries in two consecutive trials.
Following this, the innovative AI-driven tools will be ready for integration into future treatment and prevention strategies.
Pilot Trial
A small-scale pilot trial will assess the general feasibility, engagement and accessibility of the coaching and exergaming tools.
Clinical Trial
A larger clinical trial will further evaluate the tools' impacts on cognitive function, quality of life and health biomarkers.
